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Description

Initial dosing typically begins at 2.5 mg once weekly for four weeks as a treatment initiation dose to improve gastrointestinal tolerability

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Hydroxocobalamin or methylcobalamin are preferred alternatives in such cases

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Mechanisms of Disease: metabolic effects of growth hormone and insulin-like growth factor 1

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For instance, hydroxycobalamin is stored in the body longer than cyanocobalamin, reducing the need for frequent injections

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